Wednesday, 27 May 2009

Scholarship in University of Luxembourg

The University of Luxembourg is looking within the Life Sciences Research Unit (LSRU) of its Faculty of Science, Technology and Communication for a:
PhD student in systems biology (M/F)
3-year fixed term contract, renewable 1 year, beginning October 1st, 2009 at the earliest
AFR (Aide à la formation recherche) Grant

The objective of the Life Sciences Research Unit (LSRU) is to implement and to use systems biology approaches to gain further insights in characteristics of inflammatory processes occurring in Alzheimer's disease, the metabolic syndrome and cancer. Diseases occur not only from an internal dysfunction of the complex constitutive interactions between genes, their expression products and their functions, but also from numerous external disturbing interferences, e.g. exposure to cytokines or to a variety of environmental factors, including nutrients originating from food intake.
A lifetime exposure to micronutrients and cytokines may therefore be part of a central molecular process towards atherosclerosis. We propose here a feasibility study, in view to adapt the competences and possible techniques of the LSRU to a Medium Throughput Screening concept and to collect genomic, transcriptomic, simple proteomic and functional data from wet lab in vitro cellular inflammation processes, in order to evidence new genetic biomarkers in atherosclerosis. We will use systems biology and bioinformatics approaches to unify data derived from our own experiments and others reported in the literature and databases with clinical data, to generate in silico models of nuclear receptor and NF-kappaB pathways in metabolism, cellular regulation and inflammation.

Profil
Master in Bioinformatics / Biology or equal required
Knowledge in bioinformatics and experience in wet lab and genome biology are desired
Good knowledge in English
Additional French and/or German would be ideal

Application End: 02 June 2009
The University of Luxembourg is an equal opportunity employer.

Kontaktdaten
Kontakt für Bewerbungen:
Prof. Dr. Jean-Luc Bueb
E-Mail: jean-luc.bueb@uni.lu
University of Luxembourg, Life Sciences Research Unit: Systems Biology
162 A, avenue de la Faïencerie
L-1511 Luxembourg




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